Auto-Brewery Syndrome: Science, Toxicology, and the Law
Part 6: Evaluating Alternative Explanations
Counterpoint Volume 10: Issue 1 - Article 6 (August 2026)
Jan Semenoff, BA, EMA
Forensic Criminalist
Abstract
Alternative scientific explanations frequently arise in impaired driving and other forensic cases involving reported alcohol or drug findings. Whether the proposed explanation involves Auto-Brewery Syndrome, gastroesophageal reflux disease (GERD), diabetic ketoacidosis, nutritional ketosis, inhaled medications, environmental exposures, or another physiological or analytical factor, the underlying scientific question remains the same: How should competing explanations be evaluated objectively?
This article examines the principles of applying the scientific method to forensic evidence, emphasizing the distinction between scientific plausibility and scientific support. Using a recently published clinical investigation involving suspected Auto-Brewery Syndrome as an illustrative example, the discussion explores the importance of competing hypotheses, objective investigation, and evidence-based reasoning when evaluating alternative explanations.
As the concluding article in this six-part series, the discussion extends beyond Auto-Brewery Syndrome to present a broader framework for evaluating alternative scientific explanations encountered in forensic practice. Using a recently published clinical investigation as an illustrative example, the article explores the importance of competing hypotheses, objective investigation, and evidence-based reasoning when assessing alternative explanations.
(Requires a subscription to Volume 10, or DUIDLA access)
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Counterpoint Volume 10Counterpoint Volume 10 explores the science, controversies, and emerging issues shaping modern alcohol and drug testing. Through expert analysis and real-world courtroom applications, it equips legal and forensic professionals with the knowledge needed to challenge evidence and strengthen their cases. |